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Barbiturates will not impair ordinary hepatic functionality but are revealed to induce liver microsomal enzymes, Hence escalating and/or altering the metabolism of barbiturates and other drugs (see PRECAUTIONS - Drug Interactions ).Barbiturates are absorbed in various levels next oral or parenteral administration. The salts are more fast absorbed t
Nonteratogenic Effects. Reviews of infants suffering from extended-phrase barbiturate publicity in utero involved the acute withdrawal syndrome of seizures and hyperirritability from beginning to the delayed onset of up to fourteen times (see DRUG ABUSE AND DEPENDENCE).Phenobarbital is additionally contraindicated in sufferers with marked impairmen